Mitochondrial respiratory chain dysfunction variably increases oxidant stress in Caenorhabditis elegans
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چکیده
منابع مشابه
Mitochondrial respiratory chain deficiency in Caenorhabditis elegans results in developmental arrest and increased life span.
The growth and development of Caenorhabditis elegans are energy-dependent and rely on the mitochondrial respiratory chain (MRC) as the major source of ATP. The MRC is composed of approximately 70 nuclear and 12 mitochondrial gene products. Complexes I and V are multisubunit proteins of the MRC. The nuo-1 gene encodes the NADH- and FMN-binding subunit of complex I, the NADH-ubiquinone oxidoreduc...
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ژورنال
عنوان ژورنال: Mitochondrion
سال: 2010
ISSN: 1567-7249
DOI: 10.1016/j.mito.2009.11.003